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. Author manuscript; available in PMC: 2023 May 10.
Published in final edited form as: Neuroscience. 2022 Mar 21;490:275–286. doi: 10.1016/j.neuroscience.2022.03.022

Figure 3. Hippocampal cytokine expression.

Figure 3.

Box and whisker plots show the median fold change and the 25th and 75th quartiles, with the 5th and 95th percentile shown by the whiskers. Long-term exercise increased hippocampal IL-10 expression in aged mice (A). IL-33 was elevated in aged controls (Aged CON) and aged short-term (aged ST Ex), but not aged long-term (Aged LT Ex), exercise mice relative to young controls (Young CON; B). Aged mice had increased IL-β (C) and IL-6 (F) relative to young controls, but exercise had no effect. There was no difference in expression of IL-1rl1 (E) or IL-10ra (D). Dots represent individual data points within groups. Symbols indicate a significant difference from young control (*) or aged control (^).