Time-over-threshold energy estimation. Simulated pulse shapes of various amplitudes crossing the low (T1) and high (T3) thresholds. The measured time difference between T3 and T1 is an effective estimate of the pulse area (energy). Crossing the T2 threshold insures a valid pulse. Figure from LabPETII (2012 Design of a real-time FPGA-based DAQ architecture for the LabPET II). Adapted with permission from “Design of a real-time FPGA-based DAQ architecture for the LabPET II, an APD-based scanner dedicated to small animal PET imaging.”, Njejimana, Larissa, et al., 2012 18th IEEE-NPSS Real Time Conference. IEEE, 2012.