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. 2022 Apr 25;12:6746. doi: 10.1038/s41598-022-10859-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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64-year-old patient with rising PSA 12.2 ng/m. Initial MRI examination: Axial T2-weighted image (A) showed a non-circumscribed, rounded, moderate hypointensity in the left lateral peripheral zone with focal discrete hypointense ADC signal (B), focal discrete hyperintense signal on high b-value DWI (C) and discrete correlating contrast enhancement in DCE (D), assessed as PI-RADS category 3. Follow-up MRI after 38 months: Axial T2-weighted image (E) showed only residual changes, no ADC reduction (F), no more hyperintense signal on high b-value DWI (G), and no contrast enhancement (H). The PSA decreased (6.6 ng/mL) and mpMRI was downgraded to PIRADS category 2.