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. 2022 Jan 1;16(5):1205–1221. doi: 10.1038/s41396-021-01119-1

Fig. 9. Schematic summary of SP-induced CRC apoptosis.

Fig. 9

Human gut-microbiome-derived propionate decreased the protein stability of EHMT2 by up-regulation of HECTD2. Subsequently, TNFAIP1 as a novel direct target of EHMT2 induced the apoptosis of colon cancer.