Evaluation of immunological characteristics of CAR-T cells
(A) LDH-Glo assay of cytotoxicity of CAR-T cells prepared with cCas12a; data are presented as the mean ± SEM derived from triplicate samples (n = 3).
(B) IFN-γ expression levels in CAR-T cells prepared with cCas12a; data are presented as the mean ± SEM derived from triplicate samples (n = 3).
(C) TNF-α expression levels in CAR-T cells prepared with cCas12a; data are presented as the mean ± SEM derived from triplicate samples (n = 3).