Table 3.
Median (IQR) and p‑value summary of overall treatment time (OTT), Dmean and V12Gy of BmP, HI, CI and GI index and modulation factor (MU/Gy). Data includes HA-plans utilizing both 120-MLC or HD-MLC
| 120-MLC | HD-MLC | |||||
|---|---|---|---|---|---|---|
| Median (IQR) | Number of fraction/plan/GTV | Median (IQR) | Number of fraction/plan/GTV | P-value | ||
| OTT with ET (min) | All fractions | 31 (20–39) | 35 | 23 (20–31) | 165 | 0.142 |
| Modulation factor (MU/Gy) | All plans | 269 (227–286) | 32 | 338 (304–382) | 182 | ≤10−10 |
| Dmean BmP (Gy) | All GTV volumes | 1.4 (0.9–1.7) | 32 | 0.9 (0.6–1.5) | 179 | 0.038 |
| Total GTV volume ≤1 cc | 0.35 (0.23–0.58) | 6 | 0.33 (0.26–0.51) | 43 | 0.819 | |
| Total GTV volume 1 cc to 5 cc | 1.06 (0.91–1.55) | 10 | 0.84 (0.64–1.10) | 64 | 0.059 | |
| Total GTV volume >5 cc | 1.57 (1.37–2.54) | 16 | 1.70 (1.12–2.23) | 72 | 0.607 | |
| V12Gy BmP (cc) | All GTV volume | 7.5 (4.4–11.2) | 32 | 5.0 (2.0–10.1) | 179 | 0.058 |
| Total GTV volume ≤1 cc | 1.80 (0.85–2.90) | 6 | 1.20 (0–80–1.70) | 43 | 0.278 | |
| Total GTV volume 1 cc to 5 cc | 6.00 (4.50–7.30) | 10 | 4.40 (2.85–5.80) | 64 | 0.081 | |
| Total GTV volume >5 cc | 11.15 (8.80–18.00) | 16 | 11.6 (7.00–21.75) | 72 | 0.812 | |
| HIRTOG (relative value) | All GTV volume | 1.3 (1.3–1.4) | 54 | 1.4 (1.3–1.5) | 284 | 0.217 |
| Individual GTV volume ≤1 cc | 1.37 (1.24–1.44) | 24 | 1.40 (1.32–1.46) | 123 | 0.171 | |
| Individual GTV volume 1 cc to 5 cc | 1.30 (1.27–1.38) | 17 | 1.37 (1.30–1.41) | 86 | 0.284 | |
| Individual GTV volume >5 cc | 1.29 (1.24–1.32) | 13 | 1.27 (1.24–1.33) | 75 | 0.545 | |
| CIPaddick (relative value) | All GTV | 0.97 (0.96–0.98) | 54 | 0.96 (0.94–0.96) | 284 | ≤10−9 |
| Individual GTV volume ≤1 cc | 0.96 (0.96–0.98) | 24 | 0.96 (0.96–0.96) | 123 | 0.011 | |
| Individual GTV volume 1 cc to 5 cc | 0.97 (0.96–0.98) | 17 | 0.96 (0.94–0.96) | 86 | ≤10−3 | |
| Individual GTV volume >5 cc | 0.98 (0.98–0.98) | 13 | 0.94 (0.94–0.97) | 75 | ≤10−4 | |
| GI (relative value) | All GTV | 3.2 (2.9–4.0) | 54 | 3.0 (2.7–3.5) | 284 | 0.025 |
| Individual GTV volume ≤1 cc | 3.93 (3.55–4.65) | 24 | 3.44 (3.11–4.01) | 123 | 0.002 | |
| Individual GTV volume 1 cc to 5 cc | 3.00 (2.90–3.21) | 17 | 3.00 (2.81–3.23) | 86 | 0.673 | |
| Individual GTV volume >5 cc | 2.67 (2.60–2.84) | 13 | 2.57 (2.43–2.68) | 75 | 0.094 | |