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Effect of a supercritical CO2A. gratissima leaves extract (EAG) on mice motor coordination (assessed by the Rota–Rod test). The animals (n = 7/group) were orally treated with vehicle (NaCl 0.9% + 1% tween 80), indomethacin (10 mg/kg) or EAG (10 mg/kg) 1 h before the test. Data are expressed as Mean ± S.E.M. Results were analyzed by Two-Way repeated measures ANOVA.
| Group | Length of stay (s) | Number of falls |
|---|---|---|
| Vehicle | 300.0 | 0.0 |
| Indomethacin | 300.0 | 0.0 |
| EAG | 299.6 ± 0.3 | 0.11 ± 0.03 |
