. 2021 Aug 12;12(3):269–280. doi: 10.1016/j.jtcme.2021.08.007

Table 2.

Serum lipid profile of experimental animals 21 days after treatment with Costus pictus methanolic and aqueous leaf extracts and their co-administration with metformin.

GROUPS	TC∗ (mg/dL)	TG (mg/dL)	HDL (mg/dL)	LDL-C (mg/dL)	VLDL-C (mg/dL)
Normal	107.78 ± 6.17^a∗∗	94.22 ± 8.38^a	45.18 ± 1.57^a	43.75 ± 7.19^a	18.85 ± 1.68^a
Diabetic	221.67 ± 24.76^b	202.67 ± 24.18^b	24.40 ± 2.76^b	156.73 ± 20.39^b	40.53 ± 4.84^b
MET	129.31 ± 13.29^a	124.38 ± 16.97^a	24.47 ± 1.35^b	79.96 ± 12.01^a	24.88 ± 3.39^a
CPAQ400	138.20 ± 16.60^a	135.44 ± 18.92^a	33.05 ± 1.90^c	78.06 ± 13.04^a	27.09 ± 3.78^a
CPME400	135.83 ± 6.45^a	133.50 ± 12.48^a	34.61 ± 1.45^c	74.52 ± 4.51^a	26.70 ± 2.50^a
CPAQ200+MET	142.78 ± 8.51^a	140.67 ± 13.90^a	31.42 ± 3.58^c	83.22 ± 8.94^a	28.13 ± 2.78^a
CPME200+MET	140.14 ± 8.90^a	138.84 ± 12.95^a	32.77 ± 2.64^c	79.61 ± 4.37^a	27.77 ± 2.59^a
CPAQ400+MET	132.78 ± 17.30^a	130.09 ± 11.49^a	36.10 ± 1.75^c	70.66 ± 16.18^a	26.02 ± 2.30^a
CPME400+MET	130.83 ± 10.74^a	126.44 ± 13.75^a	37.30 ± 1.31^c	68.24 ± 11.00^a	25.29 ± 2.75^a

The Same superscript down the column denotes no significant difference (P ≤ 0.05).

Normal = Normal Control; Diabetic = Diabetic Control; MET = Diabetic +120 mg/kg b.wt Metformin; CPAQ400 = Diabetic+400 mg/kg b.wt of aqueous C. pictus; CPME400 = Diabetic+400 mg/kg b.wt of methanolic C. pictus; CPAQ200+MET = Diabetic+(200 mg/kg b.wt of CPAQ+60 mg/kg b.wt metformin); CPME200+MET = Diabetic +(200 mg/kg b.wt of CPME+60 mg/kg b.wt metformin); CPAQ400+MET = Diabetic+(400 mg/kg b.wt of CPAQ+60 mg/kg b.wt metformin); CPME400+MET = Diabetic+(400 mg/kg b.wt of CPME+60 mg/kg b.wt metformin).

∗TC- Total Cholesterol; TG- Total Glyceraldehides; HDL- High-Density Lipoproteins; LDL- Low-Density Lipoprotein; VLDL- Very Low-Density Lipoproteins.

∗∗Values are mean of five replicates ± Standard Error of Mean (SEM).