Table 2.
Parameters measured by working heart perfusion according to Neely.
| Control | Diabetes | Diabetes + Stellaria m. |
p | |
|---|---|---|---|---|
| Aortic flow (mL) | 44.4 ± 2.6 | 27.3 ± 2.4∗ | 34.4 ± 2.3∗ | p < 0.05 |
| Coronary flow (mL) | 22.8 ± 0.7 | 21.8 ± 1.5 | 23.7 ± 1.0 | ns |
| Max dp/dt (mmHg/s) | 6323 ± 282 | 6260 ± 439 | 6431 ± 487 | ns |
| Min dp/dt (mmHg/s) | – 4520 ± 188 | – 4512 ± 397 | – 4496 ± 374 | ns |
| Aortic diastolic pressure (mmHg) | 37.6 ± 0.5 | 37.9 ± 0.8 | 37.8 ± 1.1 | ns |
| Aortic systolic pressure (mmHg) | 114.8 ± 2.5 | 110.4 ± 3.3 | 114.9 ± 3.1 | ns |
| LVDP (mmHg) | 136.2 ± 4.6 | 130.0 ± 4.5 | 131.3 ± 5.2 | ns |
| Heart rate (1/min) | 240 ± 10 | 211 ± 16 | 231 ± 11 | ns |
Results are means ± SEM (n = 8–10), analyzed by one-way ANOVA with Holm-Sidak post hoc test,∗p < 0.05 vs. Control. LVDP left ventricular developed pressure, ns non-significant.