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Effect of IPM on expression of TNF-α and IL-6 in joint tissues. Values expressed as means ± SE, n = 5, ∗P < 0.05 with RA control, #P < 0.05 with diclofenac. IPM: n-hexane-insoluble fraction of dichloromethane extracts of P. major; RA: Rheumatoid arthritis.
