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Experimental design.
| Group | Treatment |
|---|---|
| Group 1 Group 2 Group 3 Group 4 Group 5 |
Normal Control (NC) RA Control (RAC) CFA + Na diclofenac 5 mg/kg CFA + IPM 280 mg/kg BW CFA + IPM 420 mg/kg BW |
Extracts/Na diclofenac were orally administered daily from day 16–46.
IPM: n-hexane-insoluble fraction of dichloromethane extracts of P. major.
RA: Rheumatoid arthritis.
CFA: Complete Freund's Adjuvant.
