Table 2. Frequencies of severe hypersensitivity reactions to first-line anti-tuberculosis drugs.
| Severe hypersensitivity reactions | INH | RIF | ETB | PZA | Sum |
|---|---|---|---|---|---|
| Acute generalized exanthematous pustulosis | 1 (100.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 |
| Anaphylactic reaction | 0 (0.0) | 1 (100.0) | 0 (0.0) | 0 (0.0) | 1 |
| Drug hypersensitivity syndrome | 4 (21.1) | 7 (36.8) | 5 (26.3) | 3 (15.8) | 19 |
| Hypotension | 1 (8.33) | 10 (83.3) | 1 (8.3) | 0 (0.0) | 12 |
| Stevens-Johnson syndrome | 6 (26.1) | 7 (30.4) | 6 (26.1) | 4 (17.4) | 23 |
| Sum | 12 (21.4) | 25 (44.6) | 12 (21.4) | 7 (12.5) | 56 |
INH = isoniazid, RIF = rifampicin, ETB = ethambutol, PZA = pyrazinamide.