TABLE 1.

Details of activation clusters (placebo > prucalopride) from whole brain analysis for the mean effect of task.

Cluster number	Size (voxels)	Z-max	p-value	Z-max location (MNI)	Main regions involved in cluster
6	408	4.56	<0.001	62,−2,32	R pre-central/post-central gyrus
5	299	4.6	<0.001	−62,−30,38	L supramarginal/post-central gyrus
4	242	3.65	<0.001	12,2,68	R superior frontal gyrus
3	178	2.71	0.002	6,0,50	Anterior cingulate cortex
2	116	1.68	0.021	−28,−6,12	L putamen/insula
1	106	1.5	0.032	−48,−18,42	L post-central/pre-central gyrus