Table 3.
Drugs Variation
| Medication | Baseline | 32 Weeks | 4 Years | 9 Years | 16 Years | p value |
|---|---|---|---|---|---|---|
| ICS | ||||||
| High dose | 8 | 2 | 2 | 1 | 4 | 0.031 |
| Medium dose | 0 | 6 | 5 | 2 | 4 | 0.018 |
| Low dose | 0 | 0 | 1 | 5 | 0 | 0.001 |
| OCS | 7 | 1 | 0 | 1 | 0 | <0.0001 |
| LABAs | 8 | 8 | 8 | 7 | 7 | 0.53 |
| LAMAs | 5 | 2 | 2 | 2 | 2 | 0.39 |
| LTRAs | 4 | 1 | 0 | 2 | 3 | 0.15 |
| Theophylline | 1 | 0 | 0 | 0 | 0 | 0.39 |
| SABAs | 8 | 7 | 3 | 2 | 2 | 0.002 |
Abbreviations: ICS, inhaled corticosteroids; OCS, oral corticosteroids; LABAs, long-acting beta-agonists; LAMAs, long-acting muscarinic antagonists; LTRAs, leukotriene receptor antagonists; SABAs, short-acting beta agonists.