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. 2022 Apr 12;16:800883. doi: 10.3389/fnins.2022.800883

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Copyright © 2022 Lin, Fang, Hsu, Huang, Lee, Huang, Chen, Lam and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of mitochondrial transplantation on the sensory and locomotor functions and the white matter sparing in the injured spinal cord of rats with traumatic SCI. (A) Representative micrographs of SSEP traces recorded in SCI rats on PID 28. Scale = 100 μV/5 ms (B) Quantitative results of BBB scoring. **p < 0.01, ****p < 0.0001, Sidak’s multiple comparisons performed after the repeated measures two-way ANOVA. (C) Representative micrographs of LFB staining of transverse sections prepared from the injured spinal cords of rats. Scale bar = 100 μm. The red frames indicated the analyzed areas. (D) Quantitative results of percentage of LFB-positive area. *p < 0.05, **p < 0.01, ***p < 0.001, two-tailed Student’s t-test. Data were expressed as mean ± standard deviation. N = 5. MT: mitochondria trans-plantation.