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. 2022 Apr 12;16:800883. doi: 10.3389/fnins.2022.800883

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Copyright © 2022 Lin, Fang, Hsu, Huang, Lee, Huang, Chen, Lam and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of mitochondrial transplantation on expression of pro-inflammatory cytokines in the injured spinal cord of rats with traumatic SCI on PID 1. (A) Representative micrograph of Western blots of TNF and IL-6 in sham control groups. (B,C) Quantitative results of relative expression of TNF and IL-6 in sham control groups. (D) Representative micrograph of Western blots of TNF and IL-6 in SCI groups on PID 1. (E,F) Quantitative results of relative expression of TNF and IL-6 in SCI groups on PID 1. The 1-cm spinal cord specimens centered at the epicenter of the injured site were used in Western blots. Data were expressed as mean ± standard deviation. *p < 0.05, **p < 0.01, two-tailed Student’s t-test. N = 3–5. MT, mitochondria transplantation.