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A) gp145 expression for top 12 clones in a 7-day fed-batch culture showing a high level of homogeneity in volumetric productivity at day 7. (B) Growth profile of top 3 gp145-expressing clones from 11-day shaking fed-batch cultures. Viable cell counts and percent viabilities are depicted as solid and dotted lines, respectively. (C) gp145 levels in fed-batch as measured via ELISA showing a steady increase of gp145 for all three clones.
