Table 5.

Relationships Between Various Factors and Co-Existent Frailty and Cognitive Impairment.

Factor	Citation	Statistical analysis	Finding	interpretation
Depressive Symptoms	Aguilar-Navarro, 2019 Ge, 2020 Kwan, 2019 Rivan, 2019 Rivan, 2020 Wu, 2020	Multinomial logistic regression Multinomial logistic regression Multinomial logistic regression Hierarchical binary logistic regression Stepwise binary logistic regression Multiple logistic regression	Significant association 0.007 Significant association <0.001 Adjusted model significant association = 0.002 Significant association <0.001 Significant association = 0.007 Significant association = 0.022	Greater number of depressive symptoms associated with comorbidity Presence of depression associated with comorbidity Greater number of depressive symptoms associated with comorbidity Presence of depression associated with comorbidity Greater number of depressive symptoms associated with comorbidity Greater number of depressive symptoms associated with comorbidity
Depression and anxiety	Li, 2020,	Poisson regression model	Significant association <0.001	Reporting of problems with anxiety and depression associated with comorbidity
Education level	Wu, 2020	Multiple logistic regression	Not significant association = 0.924	Years of education not associated with comorbidity
Social Support	Rivan, 2019	Hierarchical binary logistic regression	Significant association <0.001	Reported lower levels of social support associated with comorbidity