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. 2022 Apr 25;12(4):e050287. doi: 10.1136/bmjopen-2021-050287

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Histogram of number and severity of symptoms reported, number of abnormal clinical examinations, number of abnormal investigations per stage per combined study population (n=11 454).