Table 3.
Histologic features according to underlying nephropathy
| Variables | N = 26 | n = 20 | n = 6 |
|---|---|---|---|
| Glomerulus | All patients | IgAN | Non-IgAN diseases |
| Number of glomeruli per biopsy, Md (IQR) | 13 (9–20.5) | 12 (9–21.5) | 18 (11.5–20.5) |
| Glomerulosclerosis, Md (IQR), % | 10 (3–28) | 9 (1–25) | 21.5 (3.5–38.7) |
| Mesangial expansion, n (%) | |||
| None (<10%) | 6 (23.1) | 5 (25) | 1 (16.7) |
| Mild (10%–25%) | 10 (38.5) | 8 (40) | 2 (33.3) |
| Moderate (26%–50%) | 5 (19.2) | 4 (20) | 1 (16.7) |
| Diffuse (>50%) | 5 (19.2) | 3 (15) | 2 (33.3) |
| Endocapillary proliferation, n (%) | 2 (7.7) | 2 (10) | 0 (0) |
| Extracapillary proliferation, n (%) | 2 (7.7) | 2 (10) | 0 (0) |
| Focal segmental glomerulosclerosis lesions, n (%) | 7 (26.9) | 6 (30) | 1 (16.7) |
| Tubulointerstitium | |||
| Interstitial fibrosis and tubular atrophy, n (%) | |||
| None (<10%) | 0 (0) | 0 (0) | 0 (0) |
| Mild (10%–25%) | 14 (53.8) | 11 (55) | 3 (50) |
| Moderate (26%–50%) | 10 (38.5) | 9 (45) | 1 (16.7) |
| Severe (>50%) | 2 (7.7) | 0 (0) | 2 (33.3) |
| RBC casts in tubules, n (%) | 21 (80.8) | 18 (90) | 3 (50) |
| Acute tubular necrosis, n (%) | 23 (88.5) | 17 (85) | 6 (100) |
| Arterio- and arteriolosclerosis | 11 (42.3) | 8 (40) | 3 (50) |
IgAN, IgA nephropathy; IQR, interquartile range; Md, median; RBC, red blood cell.
Continuous data are expressed as Md (IQR), categorical variables as n (%).