Figure 2.

Kidney outcome by CHIP carrier status and influence of risk factors. Relative risks are presented as hazard ratios with 95% CIs. Continuous variables used to adjust models were standardized. All listed variables were used to adjust the model for CHIP and DNMT3A/TET2. The hazard ratios of the adjustment variables in the DNMT3A/TET2 model are not shown as they did not differ. The vertical axis is on a logarithmic scale. adj., adjusted; BMI, body mass index; BP, blood pressure; CAD, coronary artery disease; CD, cerebrovascular disease; CHIP, clonal hematopoiesis of indeterminate potential; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; PAD, peripheral artery disease; T2DM, type 2 diabetes mellitus; Unadj., unadjusted.