Table 3.
Malaria, SMA, and mortality stratified by genotype/haplotype across the 36-month follow-up period.
| Genotype/haplotype | Amino acid | Malaria episodes | SMA episodes | Mortality |
|---|---|---|---|---|
| 2307C>G (rs2230199) | Arg>Gly102 | Total = 7717 | Total = 444 | Total = 99 |
| CC | Arg/Arg102 | 6127 | 349 | 75 |
| CG | Arg/Gly102 | 1465 | 81 | 21 |
| GG | Gly/Gly102 | 125 | 14 | 3 |
| 34420G>A (rs11569534) | Gly>Asp1224 | Total = 7695 | Total = 442 | Total = 95 |
| GG | Gly/Gly1224 | 6763 | 385 | 82 |
| GA | Gly/Asp1224 | 494 | 36 | 7 |
| AA | Asp/Asp1224 | 438 | 21 | 6 |
| 2307C>G/34420G>A | Arg>Gly102/Gly>Asp1224 | Total = 7755 | Total = 447 | Total = 100 |
| Non-CG | Non-Arg102Non-Gly1224 | 682 | 46 | 9 |
| CG | Arg102Gly1224 | 7073 | 401 | 91 |
| Non-CA | Non-Arg102Asp1224 | 6838 | 390 | 87 |
| CA | Arg102Asp1224 | 917 | 57 | 13 |
| Non-GG | Non-Gly102Gly1224 | 6279 | 355 | 77 |
| GG | Gly102Gly1224 | 1476 | 92 | 23 |
| Non-GA | Non-Gly102Asp1224 | 7639 | 444 | 99 |
| GA | Gly102Asp1224 | 116 | 3 | 1 |
Data are presented as the number of malaria and SMA episodes, and all-cause mortality stratified according genotypes and haplotypes during the 36-month follow-up period.