Innovation technology and artificial intelligence are significantly changing the field of healthcare.

E-health is a term to describe a broad range of digital technologies and interventions used by a variety of stakeholders, across different settings.

Literature evidence shows that e-health improves the quality of care and the adherence to therapy, as well as allows early detection of worsening in chronic pulmonary diseases.

Widely agreed and standardized endpoints for conducting trials and reporting results on the role of technology in respiratory medicine are needed.

Potential pitfalls related to e-health interventions, such as patient privacy protection, data fishing, and non-compliance with regulatory positions, should be carefully considered.