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. 2022 Apr 12;12:854589. doi: 10.3389/fonc.2022.854589

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Copyright © 2022 Gaudreault, Chang, Hardcastle, Jackson, Kron, Hanna, Hofman and Siva

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A, C, E) SUV distribution and illustration of the shell method to extract SUVmax for three different patients as well as (B, D, F) resulting SUVmax as a function of the distance of the outer later from the GTV (mm). Only SUV > 1 is shown for clarity. (A) The lesion was isolated from any other functional region, and (B) SUVmax decreased or was constant. (C) The bladder was located within 10 mm of the lesion, and (D) SUVmax increased in the first 5 mm from the lesion. (E) The ureter was in the first 5 mm from the lesion, and (F) SUVmax increased up to 15 mm away from the lesion.