. 2022 Apr 12;9:840648. doi: 10.3389/fnut.2022.840648

TABLE 3.

Effect of ATX supplementation on the levels of serum TG, TC, HDL-C, and LDL-C in the HFD-fed mice.

	ND	HFD	Solvent	HFD+0.25% ATX	HFD+0.5% ATX	HFD+0.75% ATX
TG (mmol/L)
0 day	0.41 ± 0.09^a	0.43 ± 0.18^a	0.45 ± 0.28^a	0.44 ± 0.23^a	0.43 ± 0.10^a	0.42 ± 0.11^a
30 days	0.48 ± 0.08^a	0.72 ± 0.07^b	0.70 ± 0.14^ab	0.64 ± 0.05^ab	0.54 ± 0.08^ab	0.45 ± 0.18^ab
60 days	0.47 ± 0.13^a	0.83 ± 0.12^c	0.78 ± 0.21^ab	0.74 ± 0.10^b	0.69 ± 0.15^ab	0.65 ± 0.14^ab
TC (mmol/L)
0 day	3.40 ± 0.28^a	3.49 ± 0.10^a	3.47 ± 0.13^a	3.36 ± 0.23^a	3.38 ± 0.18^a	3.30 ± 0.10^a
30 days	3.36 ± 0.08^a	4.19 ± 0.49^b	4.08 ± 0.34^b	3.56 ± 0.33^ab	3.29 ± 0.30^a	3.26 ± 0.57^a
60 days	3.39 ± 0.12^a	4.73 ± 0.38^b	4.35 ± 0.41^b	3.65 ± 0.18^a	3.16 ± 0.09^a	2.94 ± 0.38^a
HDL-C (mmol/L)
0 day	0.59 ± 0.08^a	0.60 ± 0.06^a	0.62 ± 0.12^a	0.60 ± 0.14^a	0.62 ± 0.09^a	0.56 ± 0.08^a
30 days	0.49 ± 0.04^a	0.36 ± 0.02^b	0.36 ± 0.05^b	0.33 ± 0.03^b	0.31 ± 0.03^b	0.31 ± 0.08^b
60 days	0.33 ± 0.04^a	0.19 ± 0.07^b	0.22 ± 0.05^b	0.23 ± 0.04^b	0.25 ± 0.02^b	0.26 ± 0.04^ab
LDL-C (mmol/L)
0 day	0.36 ± 0.04^a	0.38 ± 0.04^a	0.37 ± 0.03^a	0.37 ± 0.04^a	0.38 ± 0.04^a	0.35 ± 0.04^a
30 days	0.39 ± 0.03^a	0.83 ± 0.14^b	0.74 ± 0.10^b	0.63 ± 0.10^b	0.51 ± 0.15^ab	0.48 ± 0.12^ab
60 days	0.57 ± 0.03^a	0.91 ± 0.25^b	0.84 ± 0.14^b	0.70 ± 0.08^b	0.59 ± 0.14^ab	0.55 ± 0.12^ab

Data were expressed as mean ± SD of 6 mice in each group and were analyzed by ANOVA analysis with Duncan’s test. Mean values denoted with different superscript letters were significant differences (P < 0.05).