TABLE 2.
Studies reporting combined biological effects of hypomagnetic field and microgravity in mammals.
| Studied materials | Experimental treatments | Combined biological effects | Refs |
|---|---|---|---|
| 8-week-old male C57BL/6 mice | HMF (<300 nT)-HLU (4 weeks) | Accumulation of iron, bone loss and negative effect on the biomechanical properties of the femur | Yang et al. (2018) |
| Weighing 260 ± 10 g male SD rats | HMF (<300 nT)-HLU (4 weeks) | Expression of RANKL and serum iron concentration increase | Jia et al. (2014) |
| 6-week-old male C57BL/6 mice | HLU (4 weeks) + HMF (<300 nT, 4 weeks) | Lower bone mineral content, iron accumulation, unbalanced bone remodeling | Xue et al. (2020b) |
| Weighing 260 ± 10 g male SD rats | HMF (<300 nT)-HLU (4 weeks) | The dielectric properties of the gastrocnemius muscle are smaller than that of both alone | Ding et al. (2014b) |
| Human bronchial epithelial cells BEAS-2B | HMF (<50 nT, 1 week) + X-rays (2, 4, 6 Gy) | Cell survival increase, less DNA damage and more efficient damage repair | Xue et al. (2020a) |
“+”: sequential treatments; “-”: simultaneous treatments.