Table 4.
Results of stratified depression meta-analyses.
| Stratified analyses | Quality of the included studies | Total number of studies, N | Standardized mean difference (95% CI) | Cochran Q (df) | Cochran Q, P value | I2 (%) | |||||||||||
| Randomization type | |||||||||||||||||
|
|
Clustered [42,46,53] | 3 poor | 3 | −0.14 (−0.24 to −0.03) | 1.07 (2) | .59 | 0.0 | ||||||||||
|
|
Other [40,44,45,48,51,52,54] | 3 good; 1 fair; 3 poor | 7 | −0.26 (−0.53 to 0.01) | 18.32 (6) | .005 | 67.2 | ||||||||||
| Analysis type | |||||||||||||||||
|
|
Intention to treat [44,45,51,52] | 2 good; 1 fair; 1 poor | 4 | −0.24 (−0.56 to −0.07) | 8.29 (3) | .04 | 63.8 | ||||||||||
|
|
Other or unclear [40,42,46,48,53,54] | 1 good; 5 poor | 6 | −0.22 (−0.43 to −0.01) | 13.14 (5) | .02 | 62.0 | ||||||||||
| Intervention type | |||||||||||||||||
|
|
Treatment [40,42,45,48,51,52,54] | 2 good; 1 fair; 4 poor | 7 | −0.22 (−0.46 to 0.03) | 19.18 (6) | .004 | 68.7 | ||||||||||
|
|
Prevention [44,46,53] | 1 good; 2 poor | 3 | −0.26 (−0.43 to −0.09) | 2.12 (2) | .35 | 5.9 | ||||||||||
| Control group type | |||||||||||||||||
|
|
Treatment [45,46] | 1 fair; 1 poor | 2 | −0.17 (−0.49 to 0.14) | 1.47 (1) | .23 | 32.1 | ||||||||||
|
|
Other [40,42,44,46,48,51-54] | 3 good; 6 poor | 9 | −0.25 (−0.43 to −0.07) | 21.01 (8) | .007 | 61.9 | ||||||||||
| Study quality | |||||||||||||||||
|
|
Good [40,44,51] | 3 good | 3 | −0.10 (−0.49 to 0.29) | 4.52 (2) | .11 | 55.7 | ||||||||||
|
|
Fair [45] | 1 fair | 1 | −0.06 (−0.34 to 0.23) | N/Aa | N/A | N/A | ||||||||||
|
|
Poor [42,46,48,52-54] | 6 poor | 6 | −0.32 (−0.56 to −0.08) | 16.74 (5) | .005 | 70.1 | ||||||||||
aN/A: not applicable. Only 1 study was included in this stratification.