Table 3.
Main characteristics at diagnosis of cyst infection in 18 patients with ADPKD with functional allograft according to the location of cyst infection on imaging exams
| Native kidney cyst infection n = 12/episode n = 12 | Liver cyst infection n = 6/episode n = 7 | P Value | |
|---|---|---|---|
| Clinical features | |||
| Age, yr | 58 (7) | 64 (4) | 0.023 |
| Male | 9/12 (75%) | 1/6 (17%) | 0.043 |
| Delay between transplantation and cyst infection (mo) | 35 (36) | 37 (25) | 0.8 |
| Pre-emptive transplantation | 6/12 (50%) | 4/6 (67%) | 0.64 |
| Atypical clinical signs | 4 (33%) | 3 (43%) | 1 |
| Lack of fever | 1 (8%) | 1 (14%) | 1 |
| Isolated fever | 3 (25%) | 2 (29%) | 1 |
| Severe sepsis/septic shock | 1 (8%) | 2 (29%) | 0.52 |
| Laboratory findings | |||
| Leukocyte (G/l) | 8.5 (4.2) | 7.9 (3.8) | 0.76 |
| Polynuclear neutrophils (G/l) | 6.8 (3.5) | 6.1 (3.4) | 0.71 |
| C-reactive protein (mg/l) | 150 (75) | 184 (62) | 0.31 |
| Acute kidney injury | 7 (58%) | 5 (71%) | 0.66 |
| AKIN 1 | 3 (43%) | 3 (60%) | 1 |
| AKIN 2 | 1 (14%) | 1 (20%) | 1 |
| AKIN 3 | 3 (43%) | 1 (20%) | 0.58 |
| Microbiological features | |||
| Positive culture | 10 (83%) | 3 (43%) | 0.13 |
| Cyst fluid | 1 | 1 | |
| Blood culture | 4 | 3 | |
| Urine culture | 6 | — | |
| Microbial identification | |||
| Gram-negative bacilli | 7 (70%) | 3 (100%) | 0.53 |
| Escherichia coli | 4 (40%) | 1 (33%) | 1 |
| Others | 3 (30%)a | 2 (67%)b | 0.51 |
| Gram positive bacteria | 3 (30%) | 0 (0) | 0.53 |
| Enterococcus faecalis | 1 (10%) | — | |
| Streptococcus species | 2 (20%) | — |
ADPKD, autosomal dominant polycystic kidney disease.
Continuous variables were summarized as mean and SD, and categorical and ordinal variables were summarized as frequencies and percentages.
a
Morganella morganii n =1, Pseudomonas aeruginosa n = 1 and Bacillus licheniformis n = 1.
b
Klebsiella oxytoca n =1 and Enterobacter cloacae n = 1