Table 2.

Clinical features at the time of renal biopsy according to the density of lymphatic vessels in 76 patients with IgA nephropathy

Feature	Total	Density of lymphatic vessels <8 per mm2	≥8 per mm2	P
Age, yra	41 (30–49)	41 (30–52)	32 (27–48)	0.36
Sex, males/females	48 (74%)/17	42 (78%)/12	6(55%)/5	0.11
Comorbidities
Hypertension	25 (33%)	21 (32%)	4 (36%)	0.79
Diabetes	3 (4%)	3 (5%)	0	0.47
Hepatic cirrhosis	6 (8%)	6 (9%)	0	0.29
Other	19 (25%)	15 (23%)	4 (36%)	0.55
Hematuria	62 (85%)	52 (84%)	10 (91%)	0.55
Proteinuria, g/24 ha	1.3 (0.5–2.2)	1.2 (0.4–1.8)	3.5 (2–4)	<0.001
Proteinuria > 3.5 g/24 h	9 (12%)	3 (5%)	6 (55%)	<0.001
Creatinine, mg/dla	1.2 (0.9–2.0)	1.1 (0.9–1.6)	2.8 (1.0–4.0)	0.01
eGFR, ml/min	60 (33–87)	64 (42–90)	26 (17–59)	0.008
RAS inhibition	68 (89%)	58 (94%)	10 (91%)	0.5
Steroids	16 (21%)	12 (19%)	4 (36%)	0.5

eGFR, estimated glomerular filtration rate; RAS, renin-angiotensin system.

^aMedian (interquartile range).