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. 2021 Mar 2;19(4):619–628. doi: 10.1016/j.gpb.2020.10.007

Table 2.

Speed performance of GLM with and without using block matrix multiplication strategy

No. of covariates Time (s)
Without using block matrix multiplication strategy With using block matrix multiplication strategy
0 1012 597
3 2853 614
5 4908 623
10 10,837 681

Note: 0, 3, 5, and 10 covariates are added in both PLINK v1.9 and rMVP for testing speed of GLM with and without using block matrix multiplication strategy, respectively. A dataset including 16,000 samples with 1,600,000 SNPs is generated by PLINK software and used for test. All tests are performed using single thread. GLM, general linear model.