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. 2022 Mar 16;85(4):910–916. doi: 10.1021/acs.jnatprod.1c01024

Table 4. P-gp Efflux Pump Inhibitory Activity of Compounds 1–3, 5, and 6 against MDR COLO 320 Colon Adenocarcinoma Cells.

sample conc., μM FAR
tariquidara 0.2 5.533
pholiol A (1) 20 3.418
pholiol B (2) 20 6.880
pholiol C (3) 20 0.967
compound 5 20 6.638
ergosterol (6) 2 1.053
DMSO 2.00% 0.828
a

Positive control.