Table 1.
Baseline Characteristics by Cancer Status During Follow-Up
| Cancer (n = 224,016) | No Cancer (n = 4,295,227) | |
|---|---|---|
| Age, y | 56 (43-67) | 34 (23-49) |
| Female | 56.8 | 48.5 |
| Material deprivation quintile | 3 (2-4) | 3 (2-4) |
| Rural dwelling | 12.1 | 10.1 |
| Distance to health care, km | ||
| Cancer center | 25 (10-55) | 25 (10-45) |
| Family doctor | 5 (5-5) | 5 (5-5) |
| Cardiovascular comorbidities | ||
| Dyslipidemia | 24.1 | 22.2 |
| Hypertension | 31.7 | 10.7 |
| Severe obesity | 17.1 | 11.2 |
| Diabetes | 10.1 | 3.6 |
| Prior stroke or transient ischemic attack | 4.6 | 1.6 |
| Heart failure | 3.2 | 1.1 |
| Atrial fibrillation | 3.0 | 1.0 |
| Myocardial infarction | 2.1 | 0.6 |
| Peripheral artery disease | 1.0 | 0.3 |
| Noncardiovascular comorbidities | ||
| Chronic pain | 15.1 | 7.9 |
| Depression | 7.8 | 4.9 |
| COPD | 10.1 | 3.5 |
| Hypothyroidism | 7.3 | 3.2 |
| Osteoporosis | 6.9 | 2.8 |
| Gout | 5.8 | 2.1 |
| Alcohol misuse | 2.3 | 1.2 |
| Asthma | 2.1 | 1.1 |
| Irritable bowel syndrome | 1.5 | 0.8 |
| Epilepsy | 1.2 | 0.7 |
| Rheumatoid arthritis | 1.8 | 0.6 |
| Dementia | 0.7 | 0.6 |
| Schizophrenia | 0.7 | 0.5 |
| Inflammatory bowel disease | 0.8 | 0.4 |
| Multiple sclerosis | 0.7 | 0.3 |
| Severe constipation | 0.5 | 0.3 |
| Psoriasis | 0.6 | 0.3 |
| Severe chronic kidney disease | 0.4 | 0.2 |
| Parkinson’s disease | 0.4 | 0.2 |
| Peptic ulcer disease | 0.2 | 0.1 |
| Cirrhosis | 0.2 | 0.0 |
| Chronic hepatitis B | 0.1 | 0.0 |
Values are median (IQR) or %. All characteristics were obtained at baseline. Participants in the cancer group developed cancer at some point during follow-up. The following variables were missing data: material deprivation quintile (14.3%), rural dwelling (12.8%), distance to cancer center (14.2%), family doctor (13.2%), severe obesity (32.9%), and dyslipidemia (36.4%).
COPD = chronic obstructive pulmonary disease.