Table 1.
Demographic, Lifestyle, and Clinical Characteristics of the Study Sample of Invasive Breast Cancer Survivors (N = 2,272)
| Age at breast cancer diagnosis, y | |
| 51-64 | 462 (20.3) |
| 65-69 | 386 (17.0) |
| 70-74 | 580 (25.5) |
| 75-79 | 444 (19.5) |
| 80-99 | 400 (17.6) |
| Year of breast cancer diagnosis | |
| 1994-1999 | 416 (18.3) |
| 2000-2004 | 744 (32.7) |
| 2005-2009 | 490 (21.6) |
| 2010-2014 | 416 (18.3) |
| 2015-2018 | 206 (9.1) |
| Characteristics at enrollment in the Women’s Health Initiative | |
| Race | |
| American Indian/Alaska Native | 8 (0.4) |
| Asian/Pacific Islander | 27 (1.2) |
| Black/African American | 650 (28.6) |
| White | 1475 (64.9) |
| More than one race | 42 (1.8) |
| Unknown/not reported | 70 (3.1) |
| Hispanic/Latina ethnicity | |
| No | 2033 (89.5) |
| Yes | 234 (10.3) |
| Unknown/not reported | 5 (0.2) |
| Education | |
| High school diploma/GED or less | 526 (23.2) |
| School after high school | 934 (41.1) |
| College degree or higher | 794 (34.9) |
| Unknown | 18 (0.8) |
| Family income | |
| <$20,000 | 391 (17.2) |
| $20,000-$49,999 | 1,063 (46.8) |
| $50,000-$74,999 | 422 (18.6) |
| ≥$75,000 | 274 (12.1) |
| Unknown | 122 (5.4) |
| Family history of myocardial infarction or stroke | |
| No | 730 (32.1) |
| Yes | 1,477 (65.0) |
| Unknown | 65 (2.9) |
| Alcohol intake | |
| Nondrinker/past drinker | 730 (32.1) |
| <7 drinks per week | 1,273 (56.0) |
| 7+ drinks per week | 238 (10.5) |
| Unknown | 31 (1.4) |
| Antihypertensive use | |
| ACE inhibitor/ARB use | 191 (8.4) |
| Beta blocker use | 134 (5.9) |
| Calcium channel blocker use | 253 (11.1) |
| Diuretic use | 359 (15.8) |
| Characteristics assessed before breast cancer diagnosisa | |
| Ever smoked | |
| No | 1,166 (51.3) |
| Yes | 1,104 (48.6) |
| Unknown | 2 (0.1) |
| Body mass index, kg/m2 | |
| <25 | 390 (17.2) |
| 25-<30 | 755 (33.2) |
| ≥30 | 1,124 (49.5) |
| Unknown | 3 (0.1) |
| Waist circumference ≥88 cm | |
| No | 932 (41.0) |
| Yes | 1,338 (58.9) |
| Unknown | 2 (0.1) |
| Waist-to-hip ratio >0.85 | |
| No | 1,418 (62.4) |
| Yes | 852 (37.5) |
| Unknown | 2 (0.1) |
| Leisure time physical activity, MET h/wk | |
| 0 | 490 (21.6) |
| >0-<9.0 | 866 (38.1) |
| ≥9.0 | 872 (38.4) |
| Unknown | 44 (1.9) |
| History of statin use | 607 (26.7) |
| History of nonsteroidal anti-inflammatory drug use | 1,265 (55.7) |
| History of hypertensionb | 1,718 (75.6) |
| History of treated diabetes | 422 (18.6) |
| History of myocardial infarction | 76 (3.3) |
| Tumor characteristics | |
| Summary stage | |
| Localized | 1,649 (72.6) |
| Regional/distant | 587 (25.8) |
| Unknown | 36 (1.6) |
| Hormone receptor status | |
| ER+/PR+ | 1,407 (61.9) |
| ER−/PR− | 343 (15.1) |
| Mixed | 362 (15.9) |
| Unknown | 160 (7.0) |
Values are n (%).
ACE = angiotensin-converting enzyme; ARB = angiotensin receptor block; ER = estrogen receptor; MET = metabolic equivalent; PR = progesterone receptor.
a
For variables collected at multiple time points, the data presented were collected at the time point most proximal and before breast cancer.
b
A history of hypertension was ascertained through any of the following: study measurement of blood pressure at clinic visits, self-report of hypertension diagnosis, or report of antihypertensive treatment