Skip to main content

View full-text article in PMC

. 2022 Jan 18;4(1):98–109. doi: 10.1016/j.jaccao.2021.11.007

Table 3.

Mortality Rates per 1000 Person-Years in HF Patients vs Control Subjects for the Most Common Cancers

	<70 Years of Age (n = 53,611)			70-79 Years of Age (n = 60,806)			≥80 Years of Age (n = 66,619)			Total (N = 181,036)
	HF Patients	Control Subjects	HR (95% CI)	HF Patients	Control Subjects	HR (95% CI)	HF Patients	Control Subjects	HR (95% CI)	HF Patients	Control Subjects	HR (95% CI)
	IR (95% CI)	IR (95% CI)	HR (95% CI)	IR (95% CI)	IR (95% CI)	HR (95% CI)	IR (95% CI)	IR (95% CI)	HR (95% CI)	IR (95% CI)	IR (95% CI)	HR (95% CI)
Any death	30.94 (30.22-31.68)	4.34 (4.07-4.62)	7.33 (6.85-7.83)^a	85.44 (84.12-86.78)	32.81 (32.00-33.63)	2.48 (2.41-2.56)^a	241.25 (238.40-244.13)	174.05 (171.66-176.49)	1.31 (1.29-1.34)^a	96.13 (95.29-96.98)	51.05 (50.45-51.66)	2.00 (1.97-2.03)^a
Any cancer	4.71 (4.44-5.01)	0.63 (0.54-0.75)	7.54 (6.33-8.98)^a	10.35 (9.89-10.82)	2.68 (2.46-2.93)	3.80 (3.44-4.19)^a	15.67 (14.95-16.41)	4.81 (4.42-5.23)	3.10 (2.81-3.43)^a	9.11 (8.85-9.37)	2.27 (2.14-2.40)	4.11 (3.86-4.38)^a
Colorectal	0.46 (0.38-0.56)	0.09 (0.06-0.14)	5.16 (3.19-8.35)^a	1.00 (0.86-1.15)	0.36 (0.29-0.46)	2.58 (1.95-3.42)^a	2.06 (1.81-2.35)	0.83 (0.68-1.01)	2.21 (1.73-2.84)^a	1.00 (0.92-1.09)	0.35 (0.30-0.40)	2.92 (2.47-3.46)^a
Lung	1.42 (1.27-1.58)	0.12 (0.09-0.18)	11.83 (8.03-17.42)^a	2.62 (2.40-2.86)	0.41 (0.33-0.51)	6.71 (5.28-8.54)^a	2.23 (1.97-2.52)	0.39 (0.29-0.53)	6.32 (4.58-8.71)^a	2.02 (1.91-2.15)	0.28 (0.24-0.33)	7.41 (6.24-8.79)^a
Female breast	0.26 (0.17-0.40)	0.07 (0.03-0.15)	3.92 (1.60-9.65)^a	0.74 (0.60-0.94)	0.34 (0.25-0.47)^b	1.95 (1.30-2.93)^b	1.40 (1.16-1.70)	0.77 (0.60-1.00)	1.43 (1.01-2.01)^c	0.77 (0.67-0.89)	0.37 (0.30-0.45)	2.03 (1.59-2.58)^a
Male reproductive system	0.24 (0.17-0.34)	0.09 (0.05-0.15)	2.52 (1.29-4.91)^b	1.30 (1.08-1.57)	0.81 (0.64-1.02)	1.36 (0.99-1.86)	4.22 (3.62-4.92)	2.08 (1.68-2.59)	1.71 (1.29-2.26)^b	1.19 (1.07-1.34)	0.62 (0.53-0.73)	1.94 (1.60-2.35)^a
Lymphoma	0.14 (0.10-0.19)	0.01 (0.00-0.04)	15.59 (3.72-65.34)^a	0.28 (0.21-0.37)	0.09 (0.06-0.14)^c	2.65 (1.51-4.66)^b	0.27 (0.19-0.39)	0.09 (0.05-0.16)	2.84 (1.35-5.94)^b	0.22 (0.18-0.26)	0.05 (0.04-0.08)	3.92 (2.60-5.90)^a
Multiple myeloma	0.12 (0.08-0.18)	0.01 (0.00-0.03)	26.43 (3.58-194.80)^a	0.29 (0.22-0.38)	0.08 (0.05-0.13)	3.48 (1.94-6.23)^a	0.50 (0.38-0.64)	0.12 (0.07-0.21)	4.04 (2.22-7.37)^a	0.26 (0.22-0.31)	0.06 (0.04-0.08)	4.70 (3.16-6.99)^a

HF = heart failure; IR = incidence rate.

^a

P < 0.001.

^b

P < 0.005.

^c

P < 0.05.