Table 2.
Crossover Point at Which Cardiovascular Disease Mortality Rate Equals Cancer Mortality Rate
| Cancer Site | Age Group (at Diagnosis) |
||
|---|---|---|---|
| 40-59 Years | 60-79 Years | ≥80 Years | |
| Primary malignancy | |||
| Colorectal (C18-C20) | 8.6 (8.1-13.9) | 5.4 (4.7-9.3) | |
| Lung (C34) | 17.4 (12.9-26.6) | 10.6 (7.4-22.4) | |
| Malignant melanoma (C43) | 8.5 (6.8-14.6) | 1.9 (1.5-4.5) | |
| Breast (C50) | 12.7 (11.6-21.6) | 7.1 (6.3-12.6) | |
| Uterus (C54-C55) | 11.0 (8.2-20.8) | 7.1 (6.6-13.0) | 3.9 (3.5-8.8) |
| Prostate (C61) | 8.9 (7.4-16.7) | ||
| Bladder (C67) | 4.8 (2.9-9.1) | 2.6 (2.4-3.9) | |
| Non-Hodgkin lymphoma (C82-C85) | 15.4 (10.8-24.8) | 4.7 (3.1-9.9) | |
| Leukemia (C91-C95) | 6.3 (2.9-13.1) | ||
| All malignancies | |||
| Colorectal (C18-C20) | 8.3 (7.0-13.2) | ||
| Lung (C34) | 17.1 (11.5-26.2) | ||
| Malignant melanoma (C43) | 19.6 (14.4-26.2) | 8.8 (4.1-15.2) | |
| Breast (C50) | 10.4 (8.3-15.1) | ||
| Uterus (C54-C55) | 17.5 (11.7-24.7) | 5.9 (4.4-10.3) | |
| Prostate (C61) | |||
| Bladder (C67) | 9.3 (3.9-14.1) | ||
| Non-Hodgkin lymphoma (C82-C85) | |||
| Leukemia (C91-C95) | |||
Tabulated crossover point (years, 95% CI) for each cancer site and age stratum is the point at which the predicted cardiovascular disease mortality rate equals the predicted mortality rate from the cancer. Predicted cardiovascular and cancer mortality rates over time were calculated using Poisson models including categorical age at diagnosis and time since diagnosis, and crossover points were calculated by interpolating between the time points at either side of the intersection; 95% CIs were estimated by taking the 2.5th and 97.5th percentile estimates from 200 bootstrap repetitions. Crossover points are not provided if the cardiovascular mortality rate did not equal the mortality rate from cancer within 20 years.