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. 2022 Mar 15;4(1):139–140. doi: 10.1016/j.jaccao.2021.12.002

Figure 1.

Figure 1

Risk-Versus-Dose Relationship for Anthracycline-Related Diastolic Dysfunction and Heart Failure

Curves (means with 95% confidence intervals) were obtained using equation 1, correlating risk with cardiac anthracycline accumulation, as described in the text. Diastolic dysfunction (DD) occurred after lower cumulative doses and less anthracycline accumulation than heart failure (HF).