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. 2022 Mar 21;3:42–53. doi: 10.1016/j.crimmu.2022.03.002

Table 2.

Differential diagnosis of peripheral eosinophilia.

CLASS CONDITIONS
INFECTIONS
  • -

    Parasitic (helminths, ectoparasites, Strongyloides, Toxocara Canis, etc)

  • -

    Virus (HIV, HTLV)

  • -

    Fungal (coccidiomycosis)

  • -

    Bacterial (Tuberculosis)

DRUG HYPERSENSITIVITY
  • -

    Antibiotics (penicillins, cephalosporins, quinolones, sulfonamides)

  • -

    NSAIDs

  • -

    Antiepileptics (valproate, phenytoin)

  • -

    Antidepressants (fluoxetine, amitriptyline)

  • -

    Antihypertensives (ACE inhibitors, B-blockers)

HEMATOLOGIC/NEOPLASTIC DISORDERS
  • -

    Systemic mastocytosis

  • -

    Solid tumors (adenocarcinoma, squamous cells carcinomas, etc)

  • -

    Hematologic malignancy (chronic myeloid leukemia, Hodgkin lymphoma)

IMMUNE DYSREGULATIONS
  • -

    Hyper-IgE-syndrome

  • -

    Kimura disease

  • -

    Sarcodosis

  • -

    Inflammatory bowel diseases

  • -

    IgG4-related disease

  • -

    Autoimmune lymphoproliferative syndrome

COMMON ALLERGIC DISORDERS
  • -

    Allergic rhinitis, asthma, atopic dermatitis, etc.

  • -

    Allergic Bronchopulmonary Aspergillosis

OTHERS