Immunity assessment following direct injection of the OVA protein
(A) Schematic diagram showing the vaccination study design.
(B) Individual tumor measurements in animals immunized using aOVA (1μg - red line), aOVA mixed with AddaSO3™ (blue line) or AddaVax (purple line). Non-immunized mice injected with EG.7 are shown in black.
(C) Average tumor measurements for the experiment shown in (B).
(D) Kaplan Meier survival curve of the experiment displayed in (B and C).
(E) Quantification of antibody titer from the experiment shown in (A–D). For this experiment, n = 10/group with ∗p < 0.05 and ∗∗∗p < 0.001. See also Figure S4. All studies presented in (B–E) were repeated two times.