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. 2022 Apr 25;17:5. doi: 10.1186/s12263-022-00707-w

Table 3.

Results of significant association of genetic variants with components of the metabolic syndrome (diastolic blood pressure, fasting blood glucose, HDL cholesterol, and triglyceride) in Korean adultsa

No. SNP Chr Minor allele Gene DBP FBG HDL cholesterol Triglyceride
Beta ± SE Add p value Beta ± SE Add p value Beta ± SE Add p value Beta ± SE Add p value
1 rs651821 11 C APOA5 0.11 ± 0.23 0.617 0.55 ± 0.43 0.195 − 2.02 ± 0.20 1.08 × 10−22 33.44 ± 2.14 8.45 × 10−54
2 rs662799 11 G APOA5 0.12 ± 0.23 0.612 0.54 ± 0.43 0.203 − 2.02 ± 0.20 8.70 × 10−23 33.44 ± 2.14 8.26 × 10−54
3 rs2075291 11 A APOA5 0.31 ± 0.38 0.406 1.46 ± 0.71 0.040 − 3.37 ± 0.34 7.41 × 10−23 50.36 ± 3.58 2.81 × 10−44
4 rs75198898 11 A ZPR1 0.37 ± 0.38 0.327 1.43 ± 0.71 0.044 − 3.34 ± 0.34 1.59 × 10−22 49.93 ± 3.57 1.23 × 10−43
5 rs113932726 11 T ZPR1 0.37 ± 0.38 0.327 1.43 ± 0.71 0.044 − 3.34 ± 0.34 1.59 × 10−22 49.93 ± 3.57 1.23 × 10−43
6 rs3741297 11 T ZPR1 0.27 ± 0.38 0.475 1.44 ± 0.71 0.042 − 3.36 ± 0.34 7.42 × 10−23 49.95 ± 3.57 1.03 × 10−43
7 rs74368849 11 A BUD13 0.39 ± 0.38 0.303 1.41 ± 0.70 0.046 − 3.14 ± 0.34 2.79 × 10−20 47.40 ± 3.56 9.33 × 10−40
8 rs167012 5 C FBXL17 0.44 ± 0.22 0.041 1.33 ± 0.41 0.001 − 0.44 ± 0.20 0.025 8.94 ± 2.08 1.79 × 10−5

Abbreviations: SNP Single nucleotide polymorphism, Chr Chromosome, MAF Minor allele frequency, MetS Metabolic syndrome, OR Odds ratio, CI Confidence interval, SE Standard error, SBP Systolic blood pressure, DBP Diastolic blood pressure, FBG Fasting blood glucose, HDL High-density lipoprotein, Add Additive model

aModels were adjusted for age, residential area, and sex