TABLE 2.
MICs of fluoroquinolones and other drugs for S. enterica serovar Typhi strains resistant or susceptible to nalidixic acid
Drugs | MIC (μg/ml)
|
|||||
---|---|---|---|---|---|---|
Resistant strains (n = 10)
|
Susceptible strains (n = 52)
|
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Range | 50% | 90% | Range | 50% | 90% | |
Ciprofloxacin | 0.125–0.5 | 0.25 | 0.5 | 0.008–0.031 | 0.016 | 0.031 |
Ofloxacin | 0.5–1.0 | 0.5 | 1.0 | 0.031–0.25 | 0.063 | 0.25 |
Norfloxacin | 0.5–2.0 | 1.0 | 2.0 | 0.031–0.25 | 0.063 | 0.25 |
Levofloxacin | 0.25–0.5 | 0.25 | 0.5 | 0.031–0.25 | 0.063 | 0.125 |
Tosufloxacin | 0.016–0.25 | 0.125 | 0.25 | 0.004–0.25 | 0.016 | 0.016 |
Sparfloxacin | 0.016–0.25 | 0.25 | 0.25 | 0.008–0.25 | 0.016 | 0.016 |
Cefoperazone | 0.25–8.0 | 0.5 | 4.0 | 0.031–4.0 | 0.25 | 2.0 |
Ceftriaxone | 0.031–0.063 | 0.063 | 0.063 | 0.016–0.063 | 0.031 | 0.063 |
Cefotaxime | 0.031–0.063 | 0.063 | 0.063 | 0.031–0.125 | 0.063 | 0.063 |