Table 2.
Univariate analysis of the variables associated with HT in the development cohort
| HT (n = 48) | Non-HT (n = 344) | P Value | |
|---|---|---|---|
| Demographics | |||
| Age, y, median (IQR) | 71.50(62.00–77.00) | 70.00(59.25–79.00) | 0.672 |
| Age > 60 y, n (%) | 39(81.3) | 248(72.1) | 0.180 |
| Male sex, n (%) | 29(60.4) | 207(60.2) | 0.974 |
| Medical history, n (%) | |||
| Hypertension | 32(66.7) | 256(74.4) | 0.254 |
| Diabetes mellitus | 18(37.5) | 107(31.1) | 0.373 |
| Previous stroke | 7(14.6) | 46(13.4) | 0.818 |
| Atrial fibrillation | 28(58.3) | 52(15.1) | 0.000* |
| Antiplatelet | 4(8.3) | 49(14.2) | 0.262 |
| Oral anticoagulant | 3(6.3) | 10(2.9) | 0.435 |
| Smoking current | 14(29.2) | 133(38.7) | 0.203 |
| Baseline data, median (IQR) | |||
| Systolic BP, mm Hg, | 140.00(130.00–167.00) | 154.50(139.25–172.00) | 0.024* |
| Diastolic BP, mm Hg, | 81.00(75.25–92.00) | 80.00(80.00–100.00) | 0.053* |
| Temperature,°C | 36.55(36.40–36.90) | 36.50(36.40–36.68) | 0.045* |
| Glucose, mmol/L | 6.61(5.93–11.43) | 6.23(5.07–7.91) | 0.015* |
| TC, mmol/L | 4.22(3.81–5.09) | 4.83(4.11–5.47) | 0.004* |
| TG, mmol/L | 1.28(0.94–1.69) | 1.36(1.01–1.90) | 0.212 |
| HDL, mmol/L | 1.04(0.85–1.27) | 1.06(0.91–1.25) | 0.411 |
| LDL, mmol/L | 2.72 ± 0.90 | 2.91 ± 0.95 | 0.200 |
| PLT, ×109/L | 158.50(127.50–211.25) | 180.00(141.00–216.00) | 0.169 |
| PT% | 93.50(84.25–104.50) | 100.50(92.00–110.00) | 0.002* |
| APTT, s | 35.60(32.43–38.45) | 35.20(32.40–37.80) | 0.359 |
| INR | 1.04(0.97–1.11) | 1.00(0.95–1.06) | 0.009* |
| Fib, g/L | 3.59(3.08–4.66) | 3.27(2.82–3.87) | 0.003* |
| Imaging data, median (IQR) | |||
|
Cerebral Infarction Area (CIA), cm2 |
16.43(8.81–29.52) | 2.22(0.92–7.10) | 0.000* |
|
Cerebral Infarction Volume (CIV), cm3 |
32.58(15.4179.20) | 2.51(0.62–12.81) | 0.000* |
| Scores | |||
| THRIVE score, median (IQR) | 4.00(3.00–5.75) | 2.00(2.00–3.00) | 0.000* |
| NIHSS score, median (IQR) | 11.50(6.25–15.00) | 4.00(3.00–8.00) | 0.000* |
| NIHSS score > 20, n (%) | 7(14.6) | 4(1.2) | 0.000* |
| Treament | |||
| OTT, h, median (IQR) | 15.00(3.00–48.00) | 13.50(5.00–48.00) | 0.757 |
| Thrombolysis or ET, n (%) | 6(12.5) | 15(4.4) | 0.019* |
TC total cholesterol, TG triglyceride, HDL high-density lipoprotein, LDL low-density lipoprotein, PLT blood platelet, PT Prothrombin time, APTT activated partial thromboplastin time, INR international normalized ratio, Fib fibrous protein, NIHSS National Institutes for Health Stroke Scale, OTT onset-to-treatment, * p<0.1