Figure 2.

Lymphocyte subpopulations and persistence of CAR-T cells. Shown are selected lymphocyte subsets before and after the 1^st and 2^nd vaccination dose. The reference ranges for healthy controls are shown in green. In the median, the patients show absolute lymphocyte values slightly below the reference range (A), whereas the median absolute cell counts for T-helper and cytotoxic T-cells were in the lower reference range (B+C). Median NK-cells were slightly decreased (D). CAR T-cell concentrations were stable over the vaccination period (E). All but one patient showed complete B-cell aplasia (F).