Table 12.
Top GO biological processes ordered by combined score, for NHBE cells.
| GO Biological Process | p-value | c-score | Cluster |
|---|---|---|---|
| regulation of calcidiol 1-monooxygenase activity (GO:0060558) | 1.83E-03 | 1610.66 | 1 |
| pantothenate metabolic process (GO:0015939) | 1.83E-03 | 1610.66 | 1 |
| cellular response to type I interferon (GO:0071357) | 1.95E-12 | 1330.17 | 2 |
| type I interferon signaling pathway (GO:0060337) | 1.95E-12 | 1330.17 | 2 |
| postsynaptic neurotransmitter receptor internalization (GO:0098884) | 9.96E-03 | 865.07 | 2 |
| postsynaptic endocytosis (GO:0140239) | 9.96E-03 | 865.07 | 2 |
| regulation of ribonuclease activity (GO:0060700) | 9.96E-03 | 865.07 | 2 |
| response to interferon-beta (GO:0035456) | 2.28E-06 | 830.41 | 2 |
| defense response to symbiont (GO:0140546) | 9.02E-12 | 717.21 | 2 |
| defense response to virus (GO:0051607) | 1.94E-11 | 641.59 | 2 |
| response to interferon-alpha (GO:0035455) | 2.93E-04 | 593.97 | 2 |
| negative regulation of viral genome replication (GO:0045071) | 4.90E-06 | 434.32 | 2 |
| regulation of lipid storage (GO:0010883) | 5.88E-04 | 430.27 | 2 |
| antiviral innate immune response (GO:0140374) | 3.39E-03 | 426.70 | 2 |
| cytokine-mediated signaling pathway (GO:0019221) | 9.05E-15 | 395.62 | 2 |
| interleukin-27-mediated signaling pathway (GO:0070106) | 3.68E-03 | 382.07 | 2 |
| negative regulation of type I interferon-mediated signaling pathway (GO:0060339) | 4.10E-03 | 344.91 | 2 |
| negative regulation of chemokine production (GO:0032682) | 4.81E-03 | 313.53 | 2 |
| regulation of viral genome replication (GO:0045069) | 2.03E-05 | 309.60 | 2 |
| negative regulation of viral process (GO:0048525) | 2.50E-05 | 289.01 | 2 |
| regulation of complement activation (GO:0030449) | 1.88E-03 | 233.87 | 1 |
| regulation of lipid storage (GO:0010883) | 9.15E-03 | 233.65 | 1 |
| inflammatory response (GO:0006954) | 3.32E-07 | 215.82 | 2 |
| positive regulation of NIK/NF-kappaB signaling (GO:1901224) | 1.88E-03 | 213.72 | 1 |
| cellular response to virus (GO:0098586) | 2.89E-03 | 208.65 | 2 |