Table 13.
Top GO biological processes ordered by combined score, for A549 cells.
| GO Biological Process | p-value | c-score | Cluster |
|---|---|---|---|
| cellular response to type I interferon (GO:0071357) | 2.23E-15 | 1540.94 | 2 |
| type I interferon signaling pathway (GO:0060337) | 2.23E-15 | 1540.94 | 2 |
| negative regulation of viral genome replication (GO:0045071) | 3.07E-09 | 792.37 | 2 |
| response to interferon-beta (GO:0035456) | 4.98E-05 | 637.94 | 2 |
| negative regulation of viral life cycle (GO:1903901) | 1.99E-08 | 569.74 | 2 |
| regulation of viral genome replication (GO:0045069) | 2.32E-08 | 540.29 | 2 |
| regulation of interferon-alpha production (GO:0032647) | 6.90E-04 | 472.38 | 2 |
| positive regulation of interferon-alpha production (GO:0032727) | 1.26E-03 | 354.12 | 2 |
| interferon-gamma-mediated signaling pathway (GO:0060333) | 1.05E-06 | 344.39 | 2 |
| cytokine-mediated signaling pathway (GO:0019221) | 2.23E-15 | 327.50 | 2 |
| cellular response to interferon-gamma (GO:0071346) | 4.59E-08 | 321.58 | 2 |
| positive regulation of defense response to virus by host (GO:0002230) | 1.81E-03 | 300.45 | 2 |
| STAT cascade (GO:0097696) | 9.26E-04 | 211.79 | 0 |
| chemokine-mediated signaling pathway (GO:0070098) | 4.73E-04 | 195.27 | 2 |
| response to interferon-gamma (GO:0034341) | 1.78E-04 | 187.71 | 2 |
| regulation of leukocyte chemotaxis (GO:0002688) | 5.77E-03 | 169.19 | 2 |
| regulation of defense response to virus by host (GO:0050691) | 5.77E-03 | 169.19 | 2 |
| negative regulation of type I interferon production (GO:0032480) | 2.18E-03 | 160.73 | 2 |
| response to cytokine (GO:0034097) | 3.49E-05 | 147.64 | 2 |
| positive regulation of JAK-STAT cascade (GO:0046427) | 1.26E-03 | 139.37 | 2 |
| regulation of type I interferon production (GO:0032479) | 6.82E-04 | 130.07 | 2 |
| neutrophil migration (GO:1990266) | 6.25E-03 | 102.79 | 2 |
| JAK-STAT cascade (GO:0007259) | 4.73E-03 | 95.44 | 0 |
| positive regulation of leukocyte chemotaxis (GO:0002690) | 7.10E-03 | 94.66 | 2 |
| positive regulation of type I interferon production (GO:0032481) | 7.40E-03 | 92.17 | 2 |