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. 2022 Apr 25;146:105443. doi: 10.1016/j.compbiomed.2022.105443

Table 14.

Top GO biological processes ordered by combined score, for A549-ACE2 cells.

GO Biological Process p-value c-score Cluster
positive regulation of heat generation (GO:0031652) 8.32E-03 3921.08 0
regulation of fever generation (GO:0031620) 8.32E-03 3921.08 0
positive regulation of fever generation (GO:0031622) 8.32E-03 2825.38 0
regulation of vascular wound healing (GO:0061043) 8.32E-03 1765.21 0
positive regulation of steroid biosynthetic process (GO:0010893) 8.32E-03 1765.21 0
aerobic electron transport chain (GO:0019646) 3.06E-20 833.55 2
mitochondrial ATP synthesis coupled electron transport (GO:0042775) 3.06E-20 801.88 2
mitochondrial electron transport, NADH to ubiquinone (GO:0006120) 2.72E-13 692.38 2
l-phenylalanine catabolic process (GO:0006559) 4.28E-03 637.69 2
amino acid catabolic process (GO:1902222) 4.28E-03 637.69 2
ribose phosphate metabolic process (GO:0019693) 4.28E-03 637.69 2
quinone catabolic process (GO:1901662) 4.28E-03 637.69 2
cellular glucuronidation (GO:0052695) 9.25E-03 426.04 1
acyl-CoA biosynthetic process (GO:0071616) 2.56E-05 292.54 2
acetyl-CoA biosynthetic process (GO:0006085) 7.63E-04 291.06 2
NADH dehydrogenase complex assembly (GO:0010257) 3.07E-10 286.82 2
mitochondrial respiratory chain complex I assembly (GO:0032981) 3.07E-10 286.82 2
mitochondrial respiratory chain complex assembly (GO:0033108) 4.09E-10 198.40 2
l-phenylalanine metabolic process (GO:0006558) 5.27E-03 194.75 2
secondary alcohol biosynthetic process (GO:1902653) 8.13E-06 177.46 2
mitochondrial electron transport (GO:0006122) 2.48E-03 171.57 2
cholesterol biosynthetic process (GO:0006695) 1.04E-05 165.42 2
heme biosynthetic process (GO:0006783) 2.74E-04 148.92 2
fatty-acyl-CoA metabolic process (GO:0035337) 2.74E-04 148.92 2
sterol biosynthetic process (GO:0016126) 2.56E-05 135.90 2