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. 2022 Apr 25;146:105443. doi: 10.1016/j.compbiomed.2022.105443

Table 17.

Top statistically relevant GO biological processes ordered by combined score for NHBE cells using XGBoost.

GO Biological Processes p-value c-score
regulation of integrin biosynthetic process (GO:0045113) 1.32E-02 8352.53
chronic inflammatory response (GO:0002544) 1.32E-02 8352.53
peptidyl-cysteine S-nitrosylation (GO:0018119) 1.32E-02 8352.53
astrocyte development (GO:0014002) 1.32E-02 6499.56
regulation of macromolecule biosynthetic process (GO:0010556) 1.32E-02 6499.56
astrocyte differentiation (GO:0048708) 1.32E-02 5287.72
leukocyte aggregation (GO:0070486) 1.32E-02 4436.86
peptidyl-cysteine modification (GO:0018198) 1.32E-02 3808.55
defense response to fungus (GO:0050832) 3.05E-02 1111.12
glial cell development (GO:0021782) 3.05E-02 1006.18
positive regulation of intrinsic apoptotic signaling pathway (GO:2001244) 3.92E-02 589.61
regulation of intrinsic apoptotic signaling pathway (GO:2001242) 3.92E-02 425.07
inorganic anion transport (GO:0015698) 3.92E-02 405.46
positive regulation of apoptotic signaling pathway (GO:2001235) 3.92E-02 362.85
pattern recognition receptor signaling pathway (GO:0002221) 3.92E-02 347.96
antimicrobial humoral immune response (GO:0061844) 3.92E-02 327.57
neutrophil chemotaxis (GO:0030593) 3.92E-02 292.57
response to molecule of bacterial origin (GO:0002237) 3.92E-02 277.46
granulocyte chemotaxis (GO:0071621) 3.92E-02 277.46
chloride transport (GO:0006821) 3.92E-02 263.66
positive regulation of growth (GO:0045927) 3.92E-02 263.66
neutrophil migration (GO:1990266) 3.92E-02 259.33
regulation of organelle organization (GO:0033043) 3.92E-02 247.05
activation of endopeptidase activity involved in apoptotic process (GO:0006919) 3.92E-02 243.19
positive regulation of neuron projection development (GO:0010976) 3.92E-02 218.84