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. 2022 Apr 25;146:105443. doi: 10.1016/j.compbiomed.2022.105443

Table 18.

Top statistically relevant GO biological processes ordered by combined score, for A549 cells (Random Forest).

GO Biological Processes p-value c-score
RIG-I signaling pathway (GO:0039529) 2.01E-02 819.47
positive regulation of dendritic cell cytokine production (GO:0002732) 2.08E-02 658.60
cytoplasmic pattern recognition receptor signaling in response to virus (GO:0039528) 3.15E-02 463.95
positive regulation of epidermal growth factor-activated receptor activity (GO:0045741) 3.65E-02 401.14
positive regulation of vascular endothelial growth factor production (GO:0010575) 1.52E-02 314.50
regulation of vascular endothelial growth factor production (GO:0010574) 1.52E-02 280.69
positive regulation of nuclear division (GO:0051785) 1.52E-02 280.69
positive regulation of defense response to virus by host (GO:0002230) 1.52E-02 266.02
response to interferon-beta (GO:0035456) 1.52E-02 266.02
regulation of interleukin-2 production (GO:0032663) 1.52E-02 240.53
regulation of defense response to virus by host (GO:0050691) 2.02E-02 183.70
positive regulation of mitotic nuclear division (GO:0045840) 2.02E-02 183.70
positive regulation of interleukin-6 production (GO:0032755) 1.75E-02 120.65
regulation of protein localization to plasma membrane (GO:1903076) 1.97E-02 111.57
defense response to symbiont (GO:0140546) 1.52E-02 98.43
defense response to virus (GO:0051607) 1.52E-02 88.09
negative regulation of cytokine production (GO:0001818) 1.52E-02 84.74
regulation of interleukin-6 production (GO:0032675) 4.07E-02 68.02
cellular response to cytokine stimulus (GO:0071345) 1.52E-02 63.15
positive regulation of cytokine production (GO:0001819) 2.02E-02 45.00
cytokine-mediated signaling pathway (GO:0019221) 1.52E-02 38.92