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. 2022 Apr 25;146:105443. doi: 10.1016/j.compbiomed.2022.105443

Table 2.

Top 15 GO biological processes ordered by combined score after selecting differentially expressed genes using the Multi-Condition Setting (p < 0.01). GO IDs are linked to descriptions of the biological processes in the QuickGO web browser.

GO Biological Process p-value c-score
cellular response to type I interferon (GO:0071357) 2.35E-10 324.03
type I interferon signaling pathway (GO:0060337) 2.35E-10 324.03
cytokine-mediated signaling pathway (GO:0019221) 3.80E-26 319.38
protein mono-ADP-ribosylation (GO:0140289) 3.22E-04 319.17
receptor signaling pathway via STAT (GO:0097696) 2.73E-06 299.82
receptor signaling pathway via JAK-STAT (GO:0007259) 2.50E-06 250.15
exogenous peptide antigen, TAP-independent (GO:0002480) 7.04E-03 219.44
negative regulation of bone remodeling (GO:0046851) 2.62E-03 212.68
interferon-gamma-mediated signaling pathway (GO:0060333) 3.48E-08 211.38
cellular response to interferon-gamma (GO:0071346) 5.98E-10 192.56
cellular response to cytokine stimulus (GO:0071345) 6.64E-16 177.02
negative regulation of bone resorption (GO:0045779) 9.92E-03 164.52
positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) 1.39E-06 163.05
negative regulation of viral genome replication (GO:0045071) 2.50E-06 159.30
positive regulation of defense response (GO:0031349) 6.15E-08 155.70