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. 2022 Apr 25;146:105443. doi: 10.1016/j.compbiomed.2022.105443

Table 3.

Top 20 GO biological processes ordered by combined score (clustering applied over the multi-condition gene selection setting, p < 0.01). See GO IDs for links to biological processes in the QuickGo web browser.

GO Biological Process p-value c-score
type I interferon signaling pathway (GO:0060337) 4.40E-27 9111.11
cellular response to type I interferon (GO:0071357) 4.40E-27 9111.11
negative regulation of viral genome replication (GO:0045071) 1.10E-16 3820.31
defense response to symbiont (GO:0140546) 7.74E-22 3260.22
cytoplasmic PRR signaling pathwaya(GO:0039528) 1.74E-06 3253.53
negative regulation of viral process (GO:0048525) 5.16E-17 3163.10
defense response to virus (GO:0051607) 2.34E-21 2930.10
endogenous peptide antigen, TAP-independent (GO:0002486) 4.42E-05 2797.75
endogenous peptide antigen (GO:0002484) 4.42E-05 2797.75
regulation of viral genome replication (GO:0045069) 1.64E-15 2717.94
interferon-gamma-mediated signaling pathway (GO:0060333) 1.79E-15 2656.13
protein mono-ADP-ribosylation (GO:0140289) 3.35E-06 2318.71
exogenous peptide antigen, TAP-independent (GO:0002480) 6.69E-05 2159.41
cellular response to interferon-gamma (GO:0071346) 5.16E-17 2028.44
negative regulation of lipid localization (GO:1905953) 8.90E-05 1742.91
response to interferon-beta (GO:0035456) 6.88E-08 1678.71
regulation of ribonuclease activity (GO:0060700) 1.81E-03 1644.95
positive regulation of glial cell proliferation (GO:0060252) 1.81E-03 1644.95
interleukin-27-mediated signaling pathway (GO:0070106) 7.76E-06 1582.01
cytokine-mediated signaling pathway (GO:0019221) 6.11E-25 1457.27
a

Some names have been shortened in favor of succinctness, with full definitions available in the accompanying hyperlink.