Table 7.
Statistics for comparing the performance of the tested biclustering algorithms with different preprocessing techniques. Note: corresponds to the number of biclusters; is the average number of genes per bicluster; σ|I|the standard deviation of genes per bicluster; the average number of conditions per bicluster; σ|J| the standard deviation of the number of conditions per bicluster; and finally the average number of enriched terms per bicluster.
| Algorithm | Preprocessing | σ|I| | σ|J| | ||||
|---|---|---|---|---|---|---|---|
| BicPAMS | p < 0.01 | 80 | 208.03 | 18.54 | 3.16 | 0.53 | 28.91 |
| p < 0.05 | 79 | 3526.66 | 301.50 | 3.24 | 0.64 | 341.70 | |
| ANOVA (top 200) | 7 | 188.29 | 5.95 | 10.00 | 9.70 | 10.57 | |
| ANOVA (top 1000) | 20 | 676.05 | 29.13 | 5.00 | 4.22 | 55.75 | |
| ANOVA (top 5000) | 57 | 2106.18 | 128.36 | 3.61 | 1.25 | 131.32 | |
| Cheng and Church | p < 0.01 | 50 | 15.60 | 12.59 | 12.92 | 5.90 | 3.46 |
| p < 0.05 | 100 | 55.90 | 16.23 | 34.79 | 9.96 | 1.68 | |
| ANOVA (top 200) | 8 | 25.00 | 23.49 | 21.38 | 12.56 | 6.50 | |
| ANOVA (top 1000) | 56 | 17.86 | 15.27 | 17.89 | 10.67 | 4.41 | |
| ANOVA (top 5000) | 100 | 34.54 | 24.10 | 22.76 | 11.25 | 2.47 | |
| Plaid | p < 0.01 | 10 | 64.70 | 55.53 | 14.20 | 5.60 | 29.90 |
| p < 0.05 | 10 | 776.40 | 922.43 | 11.60 | 6.89 | 24.10 | |
| ANOVA (top 200) | 8 | 44.00 | 30.76 | 12.88 | 8.43 | 9.88 | |
| ANOVA (top 1000) | 10 | 159.50 | 100.72 | 12.20 | 7.29 | 18.70 | |
| ANOVA (top 5000) | 10 | 739.20 | 530.04 | 13.10 | 7.48 | 43.40 | |
| xMotifs | p < 0.01 | 10 | 31.90 | 17.17 | 8.20 | 2.86 | 1.70 |
| p < 0.05 | 10 | 654.50 | 365.82 | 6.00 | 0.00 | 6.30 | |
| ANOVA (top 200) | 6 | 30.33 | 34.30 | 24.50 | 9.73 | 10.67 | |
| ANOVA (top 1000) | 10 | 71.90 | 103.54 | 11.10 | 4.28 | 7.60 | |
| ANOVA (top 5000) | 10 | 326.00 | 538.95 | 6.20 | 0.60 | 5.30 |